Invitrogen™ PEX7 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA561908

Catalog No. PIPA561908

Description

Immunogen sequence: MSAVCGGAAR MLRTPGRHGY AAEFSPYLPG RLACATAQHY GIAGCGTLLI LDPDEAGLRL FRSFDWNDGL FDVTWSENNE HVLITCSGD Highest antigen sequence identity to the following orthologs: Mouse - 81%, Rat - 80%.

This gene encodes the cytosolic receptor for the set of peroxisomal matrix enzymes targeted to the organelle by the peroxisome targeting signal 2 (PTS2). Defects in this gene cause peroxisome biogenesis disorders (PBDs), which are characterized by multiple defects in peroxisome function. There are at least 14 complementation groups for PBDs, with more than one phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene have been associated with PBD complementation group 11 (PBD-CG11) disorders, rhizomelic chondrodysplasia punctata type 1 (RCDP1), and Refsum disease (RD).

Specifications

• Antigen: PEX7
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PEX7
• Gene Alias: MmPEX7; PBD9B; PCDP1; Peroxin 7; Peroxin-7; peroxisomal biogenesis factor 7; peroxisomal PTS2 receptor; peroxisomal targeting signal 2 receptor; peroxisome biogenesis factor 7; peroxisome targeting signal 2 receptor; Pex7; PEX7 protein; PTS2 receptor; PTS2R; RCDP1; RD
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 5191
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: O00628
• Gene Symbols: PEX7
• Immunogen: Recombinant protein corresponding to Human PEX7. Recombinant protein control fragment (Product #RP-94691).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG