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Tocris Bioscience™ PF 05089771 Available on GSA/VA Contract for Federal Government customers only.

Potent and selective Nav1.7 channel blocker

$167.40 - $699.50

Specifications

Chemical Name or Material 4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate
Molecular Formula C18H12Cl2FN5O3S2.C7H8O3S
CAS 1430806-04-4
Product Type Target: Voltage-gated Sodium Channel Blockers
Formula Weight 672.56
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
59-311-0 Available on GSA/VA Contract for Federal Government customers only. View Documents Tocris Bioscience™
5931/10
10mg Each for $167.40
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59-315-0 View Documents Tocris Bioscience™
5931/50
50mg Each for $699.50
Add to cart
 
Description

Description

Potent and selective Nav1.7 channel blocker (IC50 = 8, 11 and 171 nM for mouse, human and rat Nav1.7, respectively). Exhibits selectivity for Nav1.7 over other Nav1 channels (IC50 values are 0.11, 0.16, 0.85, 10, 11 and 25 μM for Nav1.2, Nav1.6, Nav1.1, Nav1.4, Nav1.3 and Nav1.5, respectively). Also exhibits selectivity over a panel of 81 other ion channels, receptors, enzymes and transporters. Blocks spontaneous firing of inherited erythromelalgia (IEM)-derived iPSC sensory neurons in vitro.

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Specifications

Specifications

4-[2-(3-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-4-thiazolylbenzenesulfonamide tosylate
1430806-04-4
672.56
C18H12Cl2FN5O3S2.C7H8O3S
Target: Voltage-gated Sodium Channel Blockers
Safety and Handling

Safety and Handling

Recommended Storage : Desiccate at RT

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