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Tocris Bioscience™ PF 05175157

Acetyl-CoA carboxylase (ACC) 1 and 2 inhibitor

Supplier:  Tocris Bioscience™ 5790/50

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Catalog No. 57-905-0


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Description

Description

PF 05175157 is an potent acetyl-CoA carboxylase (ACC) 2 and 1 inhibitor (IC50 values are 45 and 98 nM, respectively). Reduces hepatic and skeletal muscle malonyl-CoA levels in rats. Also inhibits hepatic de novo lipogenesis and reduces whole body respiratory exchange ratio in rats. Orally bioavailable.
Specifications

Specifications

1,4-Dihydro-1′-[2-methyl-1H-benzimidazol-6-yl)carbonyl]-1-(1-methylethyl)-spiro[5H-indazole-5,4′-piperidin]-7(6H)-one
50 mg
C23H27N5O2
>98%
1301214-47-0
Additional Lipid Metabolism Compounds
405.49
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
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