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  8. PF 670462, Tocris Bioscience™

PF 670462, Tocris Bioscience™

Catalog Number 331650
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
950912-80-8
C19H22Cl2FN5
410.318
PSNKGVAXBSAHCH-UHFFFAOYSA-N
unii-d68ans5i8b, d68ans5i8b, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl-2-pyrimidinaminedihydrochloride, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl-2-pyrimidinamine dihydrochloride, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl pyrimidin-2-amine dihydrochloride, 4-3-cyclohexyl-5-4-fluorophenyl imidazol-4-yl pyrimidin-2-amine;dihydrochloride, c19h20fn5.2clh, 2-pyrimidinamine, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl-, hydrochloride 1:2, 4-3-cyclohexyl-5-4-fluorophenyl imidazol-4-yl pyrimidin-2-amine dihydrochloride
51049607
CHEBI:87236
4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine;dihydrochloride
C1CCC(CC1)N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F.Cl.Cl
This item is not returnable. View return policy
950912-80-8
C19H22Cl2FN5
410.318
PSNKGVAXBSAHCH-UHFFFAOYSA-N
unii-d68ans5i8b, d68ans5i8b, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl-2-pyrimidinaminedihydrochloride, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl-2-pyrimidinamine dihydrochloride, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl pyrimidin-2-amine dihydrochloride, 4-3-cyclohexyl-5-4-fluorophenyl imidazol-4-yl pyrimidin-2-amine;dihydrochloride, c19h20fn5.2clh, 2-pyrimidinamine, 4-1-cyclohexyl-4-4-fluorophenyl-1h-imidazol-5-yl-, hydrochloride 1:2, 4-3-cyclohexyl-5-4-fluorophenyl imidazol-4-yl pyrimidin-2-amine dihydrochloride
51049607
CHEBI:87236
4-[3-cyclohexyl-5-(4-fluorophenyl)imidazol-4-yl]pyrimidin-2-amine;dihydrochloride
C1CCC(CC1)N2C=NC(=C2C3=NC(=NC=C3)N)C4=CC=C(C=C4)F.Cl.Cl

Description

Potent and selective CK1ε and CK1δ inhibitor

Potent and selective casein kinase 1ε (CK1ε) and CK1δ inhibitor (IC50 values are 7.7 and 14 nM respectively) that displays > 30-fold selectivity over 42 other common kinases. Inhibits PER protein nuclear translocation (EC50 = 290 nM) causing phase shifts in circadian rhythms and attenuates methamphetamine-stimulated locomotion in vivo.
Quantity 50 mg
Formula Weight 410.32
Percent Purity >99%
Chemical Name or Material PF 670462

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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