Invitrogen™ PF4 Monoclonal Antibody (170138)

Mouse Monoclonal Antibody

Supplier:  Invitrogen™ MA523926

Catalog No. PIMA523926

Description

In Western blots, no cross-reactivity with recombinant mouse (rm) CXCL6, recombinant human (rh) CXCL6, rhCXCL7, rmCXCL13 or rhCCL21 is observed. Reconstitute at 0.5 mg/mL in sterile PBS.

Platelet factor-4 is a 70-amino acid protein that is released from the alpha-granules of activated platelets and binds with high affinity to heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair (Eisman et al., 1990).

Specifications

• Antigen: PF4
• Classification: Monoclonal
• Concentration: 0.5 mg/mL
• Formulation: PBS with 5% trehalose and No Preservative
• Gene Accession No.: P02776
• Gene Symbols: Pf4
• Immunogen: E. coli-derived recombinant human CXCL4/PF4 Glu32-Ser101.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2b

• Applications: Flow Cytometry, Western Blot
• Clone: 170138
• Conjugate: Unconjugated
• Gene: Pf4
• Gene Alias: chemokine (C-X-C motif) ligand 4; C-X-C motif chemokine 4; Cxcl4; Endothelial cell growth inhibitor; Iroplact; oncostatin-A; PF4; PF-4; Pf4a; Platelet factor 4; Platelet factor 4, short form; RATPF4A; Scyb4
• Host Species: Mouse
• Purification Method: Protein A/G
• Regulatory Status: RUO
• Gene ID (Entrez): 5196
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized