PGAM5 Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA540106
Recommended positive controls: 293T and HepG2 cells. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.This protein displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. It has apparently no phosphoglycerate mutase activity and may be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.
|Recombit protein encompassing a sequence within the center region of human PGAM5.|
|Antigen affinity chromatography|
|0.1M tris with 0.1M glycine, 20% glycerol and 0.01% Thimerosal; pH 7|
|BXLBV68, phosphoglycerate mutase family member 5|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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