Invitrogen™ PGC1 alpha/beta Recombinant Rabbit Monoclonal Antibody (5K0F4)

Rabbit Recombinant Monoclonal Antibody

Supplier:  Invitrogen™ MA537948

Catalog No. PIMA537948

Description

Positive Samples: Mouse liver, Rat heart Immunogen sequence: VFGEIEECTV NLRDDGDSYG FITYRYTCDA FAALENGYTL RRSNETDFEL YFCGRKQFFK SNYADLDSNS DDFDPASTKS KYDSLDFDSL LKEAQRSLRR.

PGC-1 beta is a tissue specific co-activator that enhances the activity of estrogen receptor alpha. The co-activation function relies on a bipartite transcriptional activation domain and two LXXLL motifs that interact with the AR2 domain of ER-alpha in an estrogen-dependent manner. Ectopic expression of this protein has been shown to lead to increased mitochondrial number and basal oxygen consumption.

Specifications

• Antigen: PGC1 alpha/beta
• Classification: Recombinant Monoclonal
• Concentration: 1.5 mg/mL
• Formulation: PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O70343, Q811R2, Q86YN6, Q8VHJ7, Q9QYK2, Q9UBK2
• Gene Symbols: Ppargc1a, Ppargc1b
• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 699-798 of human PGC1alpha/beta (NP_0373931).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

• Applications: ELISA, Western Blot
• Clone: 5K0F4
• Conjugate: Unconjugated
• Gene: Ppargc1a
• Gene Alias: 4631412G21Rik; A830037N07Rik; ENSMUSG00000079510; ERR ligand 1; Errl1; Gm11133; LEM6; Ligand effect modulator 6; ligand effect modulator-6; L-PGC-1alpha; PERC; peroxisome proliferative activated receptor gamma coactivator 1; peroxisome proliferative activated receptor, gamma, coactivator 1 alpha; peroxisome proliferative activated receptor, gamma, coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-3ext; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B4-8a; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5; peroxisome proliferator-activated receptor gamma coactivator 1 alpha transcript variant B5-NT; peroxisome proliferator-activated receptor gamma coactivator 1 beta; peroxisome proliferator-activated receptor gamma coactivator 1-alpha; Peroxisome proliferator-activated receptor gamma coactivator 1-beta; peroxisome proliferator-activated receptor gamma coactivator 1beta-2a; peroxisome proliferator-activated receptor gamma coactivator-1 alpha; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; peroxisome proliferator-activated receptor gamma, coactivator 1 beta; Pgc1; PGC-1; pgc-1 alpha; pgc-1 beta; PGC-1(alpha); PGC-1(beta); PGC1A; PGC-1alpha; PGC-1-alpha; Pgc-1alphaa; PGC1B; PGC1beta; PGC-1beta; PGC-1-beta; PGC-1beta/ERRL1; PGC-1-related estrogen receptor alpha coactivator; PGC-1v; Pgco1; PPAR gamma coactivator variant form; PPAR Gamma Coactivator-1; PPAR gamma coactivator-1beta protein; PPARG coactivator 1 alpha; PPARG coactivator 1 beta; PPARgamma coactivator 1 beta; PPARgamma coactivator 1alpha; PPAR-gamma coactivator 1-alpha; PPAR-gamma coactivator 1-beta; Ppargc1; Ppargc1a; PPARGC-1-alpha; Ppargc1b; PPARGC-1-beta
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10891, 133522, 170826, 19017, 291567, 83516
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid