Invitrogen™ PGRMC2 Polyclonal Antibody

Goat Polyclonal Antibody

Supplier:  Invitrogen™ PA5142221

Catalog No. PIPA5142221

Description

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:1,000.

PGRMC2 (progesterone receptor membrane component 2), also known as DG6 (steroid receptor protein DG6) or PMBP (progesterone membrane-binding protein), is a single pass membrane protein belonging to the cytochrome b5 family (MAPR (membrane associated progesterone receptor) subfamily). Expressed in sperm, PGRMC2 is believed to function as a steroid receptor and may participate in the progesterone-dependent sperm acrosome reaction. PGRMC2 shares approximately 50% overall sequence identity with its close relative PGRMC1. The loss of the gene encoding PGRMC2 is associated with metastasis in uterine endocervical adenocarcinomas, implicating a potential role of PGRMC2 in the suppression of metastasis of endocervical adenocarcinomas.

Specifications

• Antigen: PGRMC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Pgrmc2
• Gene Alias: 4631434O19Rik; 5730409G06Rik; DG6; Membrane-associated progesterone receptor component 2; Pgrmc2; PMBP; progesterone membrane binding protein; Progesterone membrane-binding protein; progesterone receptor membrane component 2; steroid receptor protein DG6
• Host Species: Goat
• Purification Method: Ammonium Sulfate Precipitation
• Regulatory Status: RUO
• Gene ID (Entrez): 10424
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Flow Cytometry, Immunocytochemistry
• Concentration: 0.5 mg/mL
• Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
• Gene Accession No.: O15173
• Gene Symbols: Pgrmc2
• Immunogen: Peptide with sequence C-DEEDTKDHNKQD (aa 212-223).
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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