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  7. PHA 568487, Tocris Bioscience™

PHA 568487, Tocris Bioscience™

Catalog Number 313450
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
527680-57-5
C20H24N2O7
404.419
QYQZUGYJVHHHEE-QDSMGTAFSA-N
pha-568487 fumarate, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate, unii-xfl65583pd, 1,4-benzodioxin-6-carboxamide, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-, 2e-2-butenedioate 1:1
56972212
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide;(E)-but-2-enedioic acid
C1CN2CCC1C(C2)NC(=O)C3=CC4=C(C=C3)OCCO4.C(=CC(=O)O)C(=O)O
This item is not returnable. View return policy
527680-57-5
C20H24N2O7
404.419
QYQZUGYJVHHHEE-QDSMGTAFSA-N
pha-568487 fumarate, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-1,4-benzodioxin-6-carboxamide fumarate, unii-xfl65583pd, 1,4-benzodioxin-6-carboxamide, n-3r-1-azabicyclo 2.2.2 oct-3-yl-2,3-dihydro-, 2e-2-butenedioate 1:1
56972212
N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]-2,3-dihydro-1,4-benzodioxine-6-carboxamide;(E)-but-2-enedioic acid
C1CN2CCC1C(C2)NC(=O)C3=CC4=C(C=C3)OCCO4.C(=CC(=O)O)C(=O)O

Description

α7-selective agonist

Agonist of the α7 nicotinic acetylcholine receptor (Ki values are 44 and 2800 for α7 and 5-HT3 respectively, IC50 values are > 100 μM for α3β4 and α1β1δγ respectively, and % inhibition is < 1 and 5% for α4β2 and hERG respectively). Orally active and brain penetrant.
Quantity 50 mg
Formula Weight 404.41
Percent Purity >99%
Chemical Name or Material PHA 568487

Safety and Handling

Recommended Storage Desiccate at Room Temperature
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