Invitrogen™ PHC2 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA589939

Catalog No. PIPA589939

Description

Immunogen sequence: HFLPSEPTKW NVEDVYEFIR SLPGCQEIAE EFRAQEIDGQ ALLLLKEDHL MSAMNIKLGP ALKIYARISM LKDS; Positive Samples: DU145, HT-29, HeLa, Jurkat, 293T; Cellular Location: Nucleus.

In Drosophila melanogaster, the 'Polycomb' group (PcG) of genes are part of a cellular memory system that is responsible for the stable inheritance of gene activity. PcG proteins form a large multimeric, chromatin-associated protein complex. The protein encoded by this gene has homology to the Drosophila PcG protein 'polyhomeotic' (Ph) and is known to heterodimerize with EDR1 and colocalize with BMI1 in interphase nuclei of human cells. The specific function in human cells has not yet been determined. Two transcript variants encoding different isoforms have been found for this gene.

Specifications

• Antigen: PHC2
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Phc2
• Gene Alias: A3galt2; AA415044; D130050K19Rik; D4Ertd810e; early development regulator 2; early development regulator 2 (homolog of polyhomeotic 2); early development regulatory protein 2; Edr2; hPH2; mPH2; p36; Ph2; Phc2; polyhomeotic 2; polyhomeotic 2 protein; polyhomeotic homolog 2; polyhomeotic homolog 2 (Drosophila); polyhomeotic-like 2; polyhomeotic-like 2 (Drosophila); polyhomeotic-like protein 2
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1912
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 1.32 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: Q8IXK0
• Gene Symbols: Phc2
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 250-323 of human PHC2 (NP_0044182).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov