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PHKG2 Mouse anti-Human, Clone: OTI1F9, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526428

Catalog No. PIMA526428


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Description

Description

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway. The calcium/calmodulin-dependent kinase (CAMK) group consists of 75 kinases regulated by Ca2+/CaM and close relative family (CAMK, CAMKL, DAPK, MAPKAPK).
Specifications

Specifications

PHKG2
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P15735
GSD9C, PHK-gamma-T, PSK-C3, Phosphorylase kinase, gamma 2 (testis/liver), phosphorylase b kinase gamma catalytic chain, testis/liver isoform, phosphorylase kinase subunit gamma-2, serine/threonine-protein kinase PHKG2
Mouse
IgG2b
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5261
Immunohistochemistry (Paraffin), Western Blot
OTI1F9
Unconjugated
PHKG2
Liquid
PHKG2
Human recombit protein fragment corresponding to amino acids 1-216 of PHKG2 produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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