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Phospho-AQP2 (Ser264, Ser261) Rabbit anti-Human, Polyclonal, Bioss Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  BiossSupplier Diversity Partner BS4610R

Catalog No. 50-198-6108


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Description

Description

Aquaporin 2 (AQP2) is a hormonally regulated water channel located in the renal collecting duct. Mutations in the AQP2 gene cause hereditary nephrogenic diabetes insipidus in humans. A vasopressin induced cAMP increase results in the phosphorylation of AQP2 at serine-256 and its translocation from the intracellular vesicles to the apical membrane of principal cells. Recently, serine-261 has been identified as a novel phosphorylation site on AQP2 and levels of phosphorylated S261 have been shown to decrease with vasopressin treatment suggesting its involvement in vasopressin-dependent AQP2 trafficking.
Specifications

Specifications

Phospho-AQP2 (Ser264, Ser261)
Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Unconjugated
Aqp2
Liquid
Rabbit
IgG
100 μL
-20°C
Primary
359
Aqp2
1 μg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
P41181
ADH water channel; AQP 2; AQP CD; Aqp2; AQP-2; AQPCD; AQP-CD; aquaporin 2; aquaporin 2 (collecting duct); Aquaporin CD; Aquaporin2; Aquaporin-2; Aquaporin-CD; Aquaporine 2; Collecting duct water channel protein; cph; jpk; MGC34501; Water channel protein for renal collecting duct; water-channel aquaporin 2; WCH CD; WCHCD; WCH-CD
KLH conjugated synthetic phosphopeptide derived from human AQP2 around the phosphorylation site of Ser264/261.
Protein A
RUO
Antibody
Polyclonal
Human
SDS
Documents
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