Phospho-c-Jun (Ser63) Mouse anti-Human, Rat, Clone: GT653, Invitrogen
Mouse Monoclonal Antibody
Manufacturer: Invitrogen MA527760
Positive Control: 293T (25 µg/mL Anisomycin treatment for 30 min) Predicted Reactivity: Mouse (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5 ft.-TGA[CG]TCA-3 ft.. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
|PBS with no preservative|
|Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of c-Jun (phospho Ser63). The exact sequence is proprietary.|
|Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.|
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