Phospho-c-Met (Tyr1234, Tyr1235) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: LIFE TECHNOLOGIES 44887G
Descriptionc-Met is a receptor tyrosine kinase involved in cell migration and morphogenic differentiation which is normally expressed in cells of epithelial origin. It is activated in response to scatter factor (SF)/hepatocyte growth factor (HGF) binding, and undergoes dimerization and phosphorylation on multiple residues within the juxtamembrane, catalytic core, and cytoplasmic tail domains. c-Met contains three tyrosines (Tyr-x-x-x-Tyr-Tyr motif) within the activation loop of the catalytic domain, with full activation requiring phosphorylation of all three residues (tyrosines 1230, 1234, and 1235).
|Phospho-c-Met (Tyr1234, Tyr1235)|
|Dulbecco′s PBS with 1mg/ml BSA, 50% glycerol and 0.05% sodium azide; pH 7.3|
|A chemically synthesized phosphopeptide derived from the region of human c-Met containing tyrosines 1234 and 1235|
|Antigen Affinity Chromatography|
The Fisher Scientific Encompass Program offers items which are not part of our distribution portfolio. These products typically do not have pictures or detailed descriptions. However, we are committed to improving your shopping experience. Please use the form below to provide feedback related to the content on this product.