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Phospho-Caspase 3 (Ser150) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540260

Catalog No. PA540260


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Description

Description

This antibody is predicted to react with mouse and rat based on sequence homology.

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predomit caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer ft.s disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.
Specifications

Specifications

Phospho-Caspase 3 (Ser150)
Polyclonal
Unconjugated
CASP3
Liquid
CASP3
Synthesized peptide derived from human Caspase-3 around the phosphorylation site of S150.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
P42574
CASP3; CPP32; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; SCA-1
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
836
Documents
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