Invitrogen™ Phospho-DAB1 (Tyr232) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5104709

Catalog No. PIPA5104709

Description

Antibody detects endogenous levels of Dab1 only when phosphorylated at Tyrosine 232.

The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined.

Specifications

• Antigen: Phospho-DAB1 (Tyr232)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: DAB1
• Gene Alias: AI956902; C630028C02Rik; Dab reelin signal transducer 1; Dab, reelin signal transducer, homolog 1; Dab, reelin signal transducer, homolog 1 (Drosophila); Dab1; DAB1, reelin adaptor protein; disabled 1; disabled homolog 1; RP23-356E21.1; scm; scr; scrambler; yot; yotari
• Host Species: Rabbit
• Purification Method: sequential chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 13131, 1600, 266729
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: O75553, P97318, Q8CJH2
• Gene Symbols: DAB1
• Immunogen: A synthesized peptide derived from human DAB1(Accession O75553), corresponding to amino acid residues around phosphorylated Tyr232.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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