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Phospho-HDAC5/HDAC9 (Ser259, Ser220) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540215

Catalog No. PA540215


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Description

Description

This antibody is predicted to react with mouse based on sequence homology.

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
Specifications

Specifications

Phospho-HDAC5/HDAC9 (Ser259, Ser220)
Polyclonal
Unconjugated
HDAC5
Liquid
HDAC5, HDAC9
Synthesized peptide derived from human HDAC5/9 around the phosphorylation site of S259/220.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q9UKV0, Q9UQL6
HDAC5; KIAA0600; Histone deacetylase 5; HD5; Antigen NY-CO-9; HDAC9; HDAC7; HDAC7B; HDRP; KIAA0744; MITR; Histone deacetylase 9; HD9; Histone deacetylase 7B; HD7; HD7b; Histone deacetylase-related protein; MEF2-interacting transcription rep
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
10014, 9734
Documents
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