Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Phospho-Histone H2B (Ser14) Rabbit anti-Human, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA524699

Catalog No. PIMA524699


Add to cart

Description

Description

This antibody reacts to Histone H2B only when phosphorylated at serine 14. No cross reactivity with other phosphorylated histones. Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using Recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The nucleosomes wrap further and compact DNA into chromotin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones play a central role in transciption regulation, DNA repair, DNA replication, and chromosomal stability. H2B has a broad antibacterial activity.
Specifications

Specifications

Phospho-Histone H2B (Ser14)
Recombinant Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH 7.2-7.4
Q16778, Q5QNW6
H2B histone family, member F; H2B/f; H2B/I; H2BFA; H2BFH; H2BFL; H2BK5ac; HIST1H2BC; histone 1, H2bb; Histone H2B type 1-B; Histone H2B.1; Histone H2B.f; Histone H2B.I
Rabbit
IgG
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
337873, 337874, 440689, 8339, 8346, 8349
ELISA, Immunocytochemistry, Immunofluorescence, Western Blot
RM238
Unconjugated
HIST2H2BD
Liquid
HIST1H2BG, HIST1H2BI, HIST2H2BC, HIST2H2BD, HIST2H2BE, HIST2H2BF
Phospho-peptide corresponding to Phospho-Histone H2B (Ser14).
Protein A
RUO
Antibody
Monoclonal
Human
Documents
Provide Content Correction

We continue to work to improve your shopping experience and your feedback regarding this content is very important to us. Please use the form below to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Cancel Submit

For Research Use Only