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Phospho-Histone H3 (Ser28) Rabbit anti-Human, Mouse, APC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA528010

Catalog No. PIMA528010


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Description

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using Recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The CD4 antigen is involved in the recognition of MHC class II molecules and is a co-receptor for HIV. CD4 is primarily expressed in a subset of T-lymphocytes, also referred to as T helper cells, but may also be expressed by other cells in the immune system, such as monocytes, macrophages, and dendritic cells. At the tissue level, CD4 expression may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. CD4 functions to initiate or augment the early phase of T-cell activation through its association with the T-cell receptor complex and protein tyrosine kinase, Lck. It may also function as an important mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcripts have been identified in this gene.
Specifications

Specifications

Phospho-Histone H3 (Ser28)
Recombinant Monoclonal
APC
H3F3A
Liquid
Rabbit
IgG1, kappa
100 tests
4° C
Primary
15078, 3020
Flow Cytometry
HisH3S28-D6
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P84243, P84244
H3F3A
A synthetic phospho-peptide corresponding to residues surrounding Ser28 of human phospho Histone H3
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse
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