Phospho-IP3 Receptor 1 (Ser1764) Rabbit anti-Human, Rat, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA540296
This antibody is predicted to react with human and mouse based on sequence homology.Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate. Involved in the regulation of epithelial secretion of electrolytes and fluid through the interaction with AHCYL1 (By similarity). Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by the activation of CaM kinase II, eventually leading to the activation of downstream apoptosis pathways (By similarity).
|Phospho-IP3 Receptor 1 (Ser1764)|
|Synthesized peptide derived from human IP3R-I around the phosphorylation site of S1764.|
|Antigen affinity chromatography|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|ITPR1; INSP3R1; Inositol 1; 4,5-trisphosphate receptor type 1; IP3 receptor isoform 1; IP3R 1; InsP3R1; Type 1 inositol 1,4,5-trisphosphate receptor; Type 1 InsP3 receptor|
|-20° C, Avoid Freeze/Thaw Cycles|
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