Phospho-IRS1 (Ser323) Rabbit anti-Human, Polyclonal, Invitrogen
Rabbit Polyclonal Antibody
Manufacturer: Invitrogen PA540280
This antibody is predicted to react with mouse, rat, and monkey based on sequence homology.May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
|Synthesized peptide derived from human IRS-1 around the phosphorylation site of S323.|
|Antigen affinity chromatography|
|PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4|
|IRS1; Insulin receptor substrate 1; IRS-1|
|-20° C, Avoid Freeze/Thaw Cycles|
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