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Phospho-Kir6.2 (Thr224) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540157

Catalog No. PA540157


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Description

Description

This antibody is predicted to react with mouse based on sequence homology.

This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium By similarity. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Specifications

Specifications

Phospho-Kir6.2 (Thr224)
Polyclonal
Unconjugated
KCNJ11
Liquid
KCNJ11
Peptide sequence around phosphorylation site of threonine 224 (K-T-TP-S-P) derived from Human Kir6.2.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Immunocytochemistry, Immunofluorescence, Western Blot
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Q14654
ATP-sensitive inward rectifier potassium channel 11, IKATP, IRK11, Inward rectifier K channel Kir6.2, KCNJ11, Potassium channel, inwardly rectifying, subfamily J, member 11
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
3767
Documents
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