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Phospho-MeCP2 (Ser80) Rabbit anti-Human, Rat, Unconjugated, Polyclonal, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer:  Active MotifSupplier Diversity Partner 39734

Encompass

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Catalog No. 50-199-4110


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Description

Description

MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
Specifications

Specifications

Phospho-MeCP2 (Ser80)
Western Blot
Unconjugated
Mecp2
Liquid
Rabbit
IgG
RUO
Antibody
Polyclonal
Human, Rat
Mecp2
Conc. Not Determined
whole serum with 30% glycerol and 0.035% sodium azide; pH
P51608, Q00566
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; Methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
This MeCP2 phospho Ser80 antibody was raised against a peptide containing phospho Ser80 of mouse MeCP2.
10 μL
-20°C, Avoid Freeze/Thaw Cycles
Primary
29386, 4204
SDS
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