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Phospho-MLK3 (Ser674) Rabbit anti-Human, Mouse, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540303

Catalog No. PA540303


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Description

Description

This antibody is predicted to react with human and rat based on sequence homology.

Activates the JUN N-terminal pathway. Required for serum-stimulated cell proliferation and for mitogen and cytokine activation of MAPK14 (p38), MAPK3 (ERK) and MAPK8 (JNK1) through phosphorylation and activation of MAP2K4/MKK4 and MAP2K7/MKK7. Plays a role in mitogen-stimulated phosphorylation and activation of BRAF, but does not phosphorylate BRAF directly. Influences microtubule organization during the cell cycle.
Specifications

Specifications

Phospho-MLK3 (Ser674)
Polyclonal
Unconjugated
MAP3K11
Liquid
MAP3K11
Synthesized peptide derived from human MLK3 around the phosphorylation site of S674.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q16584, Q80XI6
MAP3K11; MLK3; PTK1; SPRK; Mitogen-activated protein kinase kinase kinase 11; Mixed lineage kinase 3; Src-homology 3 domain-containing proline-rich kinase
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
26403, 4296
Documents
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