Phospho-Muscle Glycogen Synthase (Ser641) Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Catalog Number	Mfr. No.	Quantity
50-194-3868	Rockland Immunochemicals 600401B28	200 μg
50-199-1995	Rockland Immunochemicals 600401B28S	25 μL

Description

Store vial at -20°C prior to opening. Aliquot contents and freeze at -20°C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4°C as an undiluted liquid. Dilute only prior to immediate use. Phospho Glycogen Synthase pS641 antibody is directed against human muscle glycogen synthase. This phospho specific polyclonal antibody is specific for phosphorylated pS641 of human muscle glycogen synthase. Reactivity with non-phosphorylated human muscle glycogen synthase is less than 1% by ELISA. Cross reactivity with muscle glycogen synthase occurs in mouse tissue. Reactivity with muscle glycogen synthase from other sources has not been determined.

Interacts with zinc finger protein A20/TNFAIP3 and inhibits TNF-induced NF-kappa-B-dependent gene expression by interfering with an RIP-or TRAF2-mediated transactivation signal. Increases cell surface CD4(T4) antigen expression. Interacts with HIV-1 matrix protein and is packaged into virions and overexpression can inhibit viral replication. May regulate matrix nuclear localization, both nuclear import of PIC (Preintegration complex) and export of GAG polyprotein and viral genomic RNA during virion production.

Specifications

• Antigen: Phospho-Muscle Glycogen Synthase (Ser641)
• Applications: ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
• Conjugate: Unconjugated
• Host Species: Rabbit
• Target Species: Human, Mouse
• Gene Accession No.: P13807, Q9Z1E4
• Gene ID (Entrez): 14936, 2997
• Primary or Secondary: Primary
• Product Type: Antibody

• Concentration: 1 mg/mL
• Classification: Polyclonal
• Form: Liquid
• Regulatory Status: RUO
• Formulation: 0.02M potassium phosphate with 0.15M NaCl and no preservative; pH 7.2
• Gene Alias: EC 2.4.1.11; Glycogen [starch] synthase, muscle; glycogen synthase; glycogen synthase 1; glycogen synthase 1 (muscle); glycogen synthase 1, muscle; glycogen synthase 3, brain; GSY; Gys; GYS1; Gys3; MGS
• Gene Symbols: Gys1
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Gene: Gys1