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Phospho-Paxillin (Tyr118) Mouse anti-Human, Clone: GT712, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527776

Catalog No. PIMA527776


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Description

Description

Positive Control: Rat2, A431 (1 mM Pervanadate treatment for 0.5 hr) Predicted Reactivity: Mouse (100%), Chicken (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK, and p210BRC/ABL. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Paxillin associates tightly with FAK and Crk through its SH2 domain. This interaction is independent of the extracellular matrix. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation.
Specifications

Specifications

Phospho-Paxillin (Tyr118)
Monoclonal
1 mg/ml
PBS with no preservative
P49023
PXN, Paxillin (phospho Tyr118), Paxillin (phospho Tyr118), Paxillin
Mouse
IgG1
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
5829
Immunocytochemistry, Immunofluorescence, Western Blot
GT712
Unconjugated
PXN
Liquid
PXN
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human Paxillin (phospho Tyr118). The exact sequence is proprietary.
Protein G
RUO
Antibody
Monoclonal
Human
Documents
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