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Phospho-PI3K p85/p55 (Tyr467, Tyr199, Tyr464) Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA5121306

Encompass

Catalog No. PIPA5121306


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Description

Description

Positive test controls include: HeLa, C2C12. Immunogen sequence: DRLYEE

Phosphoinositide 3-kinase (PI3K, phospho PI3K) Binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Phospho PI3K is necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. During insulin stimulation, it also binds to IRS-1. Growth factors and hormones trigger this phosphorylation event, which in turn coordinates cell growth, cell cycle entry, cell migration, and cell survival.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

Phospho-PI3K p85/p55 (Tyr467, Tyr199, Tyr464)
Polyclonal
Unconjugated
PIK3R1
AA414954; AGM7; GRB1; IMD36; mitochondrial poly(ADP-ribose) glycohydrolase; MPPH; MPPH1; OTTHUMP00000009783; OTTHUMP00000009784; p50alpha; p55; p55alpha; p55-GAMMA; p55PIK; p85; p85alpha; p85-ALPHA; P85B; p85beta; p85-BETA; PARG; PARG99; phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55); phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; phosphatidylinositol 3-kinase 85 kDa regulatory subunit beta; phosphatidylinositol 3-kinase p55 subunit; phosphatidylinositol 3-kinase regulartory subunit polypeptide 2; phosphatidylinositol 3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase regulatory subunit beta; phosphatidylinositol 3-kinase regulatory subunit gamma; phosphatidylinositol 3-kinase, regulartory subunit, polypeptide 2; phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha); phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 2 (p85 beta); phosp
Rabbit
Affinity Chromatography
RUO
18708, 18709, 18710, 25513, 29741, 5295, 5296, 60664, 8503
-20° C, Avoid Freeze/Thaw Cycles
Liquid
Western Blot
0.62 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
O00459, O08908, P26450, P27986, Q63787, Q63788, Q63789, Q64143, Q92569
PIK3R1, Pik3r2, PIK3R3
A synthetic phosphorylated peptide around Y467/Y199/Y464 of human p85-alpha (NP_8526641)
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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