Invitrogen™ Phospho-PIK3CA (Ser317) Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5105113

Catalog No. PIPA5105113

Description

Antibody detects endogenous levels of PIK3CA only when phosphorylated at Tyr317.

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.

Specifications

• Antigen: Phospho-PIK3CA (Ser317)
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PIK3CA
• Gene Alias: 2.7.1.153; 6330412C24Rik; caPI3K; CLOVE; CWS5; EC:2.7.11.1; GRB1; MCAP; MCM; MCMTC; MGC142161; MGC142163; p110; p110alpha; p110-alpha; phophatidylinositol 3-kinase; phosphatidylinositol 3-kinase, catalytic, 110-KD, alpha; phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit alpha; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, alpha isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha; phosphoinositide-3-kinase catalytic alpha polypeptide; phosphoinositide-3-kinase, catalytic, alpha polypeptide; PI3K; PI3K alpha; PI3Kalpha; PI3K-alpha; pi3kca; PI3-kinase p110 subunit alpha; PI3-kinase subunit alpha; Pik3ca; PIK3R1; pk3ca; ptdIns-3-kinase p110; ptdIns-3-kinase subunit alpha; ptdIns-3-kinase subunit p110-alpha; Serine/threonine protein kinase PIK3CA
• Host Species: Rabbit
• Purification Method: Sequential Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 170911, 18706, 5290
• Content And Storage: -20°C
• Form: Liquid

• Applications: Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
• Gene Accession No.: A0A0G2K344, P42336, P42337
• Gene Symbols: PIK3CA
• Immunogen: A synthesized peptide derived from human PIK3CA(Accession P42336), corresponding to amino acid residues around phosphorylated Tyr317.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov