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Phospho-PLCG1 (Tyr783) Rabbit anti-Human, Mouse, FITC, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen MA528029

Catalog No. PIMA528029


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Description

Description

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using Recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

The mammalian Phospholipase Cg (PLCg) family has two closely related proteins, PLCg1 and PLCg2. The PLCg isozymes have the core structure domains and a unique array of domains containing an additional PH domain, two SH2 domains and one SH3 domain. In response to extracellular stimuli, such as hormones and growth factors, receptor tyrosine kinases (RTKs) phosphorylate and activate PLCg. Activated PLCg catalyzes hydrolysis of phosphatidylinositol 4,5-bisphosphate (PIP2) to produce the metabolic second messenger molecules inositol 1,4,5-triphosphate (IP3) and diacylglycerol (DAG).
Specifications

Specifications

Phospho-PLCG1 (Tyr783)
Recombinant Monoclonal
FITC
PLCG1
Liquid
Rabbit
IgG1, kappa
100 tests
4° C
Primary
18803, 5335
Flow Cytometry
PLCG1Y783-C4
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
P19174, Q62077
PLCG1
A synthetic phospho-peptide corresponding to residues surrounding Tyr783 of human phospho PLCgamma1
Protein A/G
RUO
Antibody
Monoclonal
Human, Mouse
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