Phospho-PPIG (Ser376) Rabbit anti-Human, Polyclonal, Bioss
Rabbit Polyclonal Antibody
Manufacturer: Bioss BS3461R
DescriptionStructural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. The chromo proteins are conserved in eukaryotes and lead to mitotic chromosome segregation defects. This suggests a critical function of SMC family proteins in mitotic chromosome dynamics. SMC1 and SMC3 form a heterodimeric complex required for metaphase progression in mitotic cells. Specifically this SMC1/SMC3 complex is responsible for sister chromatid cohesion during metaphase. Mutations in the gene can lead to Cornelia de Lange syndrome 2.
|Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot|
|PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH|
|AU019516; AU022200; B230312B02Rik; BOS_1662; CARS-cyclophilin; CARS-Cyp; CASP10; Clk-associating RS-cyclophilin; Cyclophilin G; CYP; LOC100341939; Matrin cyclophilin; matrin cyclophilin (matrin-cyp); Matrin-cyp; MGC133241; OTTHUMP00000204761; OTTHUMP00000204762; Peptidyl-prolyl cis-trans isomerase G; peptidylprolyl isomerase G; peptidyl-prolyl isomerase G; peptidylprolyl isomerase G (cyclophilin G); peptidyl-prolyl isomerase G (cyclophilin G); peptidylprolyl isomerase G-like; PPIase G; PPIG; Rotamase G; SCAF10; SR-cyclophilin; SRCyp; SR-cyp; SR-related CTD-associated factor 10|
|KLH conjugated synthetic phosphopeptide derived from human PPIG around the phosphorylation site of Ser376 [VS (p-S)GE].|
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