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Phospho-S6 (Ser240, Ser244) Rabbit anti-Human, Invitrogen™

Rabbit Recombinant Monoclonal Antibody

Manufacturer:  Invitrogen 701845

Catalog No. 70-184-5


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Description

Description

This antibody is predicted to react with Monkey, Mouse and Rat. Recombit rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombit rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Ribosomal protein S6 is a component of the small 40S ribosomeal subunit and belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Specifications

Specifications

Phospho-S6 (Ser240, Ser244)
Recombinant Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P62753
Ribosomal Protein S6
Rabbit
IgG
100 μg
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
6194
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot
11H14L20
Unconjugated
RPS6
Liquid
RPS6
Peptide corresponding to Human RPS6 (aa 237-247)
Protein A
RUO
Antibody
Monoclonal
Human
SDS
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