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Phospho-S6 (Ser235) Mouse anti-Human, Clone: GT4610, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527780

Catalog No. PIMA527780


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Description

Description

Positive Control: C8D30, Raw264.7, 293T (Starvation 24 hr, 20% FBS treatment for 30 min) Predicted Reactivity: Rat (100%), Zebrafish (100%), Xenopus laevis (100%), Dog (100%), Chicken (100%), Bovine (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial. For short-term storage (1-2 weeks), product can be stored at 4°C. For long-term storage, aliquot and store product at -20° C or below, avioiding multiple freeze-thaw cycles.

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Specifications

Specifications

Phospho-S6 (Ser235)
Monoclonal
1 mg/ml
PBS with no preservative
P62753
RPS6, S6, ribosomal protein S6
Mouse
IgG2a
100 μl
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Primary
6194
Western Blot
GT4610
Unconjugated
RPS6
Liquid
RPS6
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RPS6 (phospho Ser235). The exact sequence is proprietary.
Protein A
RUO
Antibody
Monoclonal
Human
Documents
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