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Phospho-SHB (Tyr246) Rabbit anti-Human, Polyclonal, Invitrogen™

Rabbit Polyclonal Antibody

Manufacturer:  Invitrogen PA540212

Catalog No. PA540212


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Description

Description

This antibody is predicted to react with mouse based on sequence homology.

Adapter protein which regulates several signal transduction cascades by linking activated receptors to downstream signaling components. May play a role in angiogenesis by regulating FGFR1, VEGFR2 and PDGFR signaling. May also play a role in T-cell antigen receptor/TCR signaling, interleukin-2 signaling, apoptosis and neuronal cells differentiation by mediating basic-FGF and NGF-induced signaling cascades. May also regulate IRS1 and IRS2 signaling in insulin-producing cells
Specifications

Specifications

Phospho-SHB (Tyr246)
Polyclonal
Unconjugated
SHB
Liquid
SHB
Synthesized peptide derived from human Shb around the phosphorylation site of Y246.
Antigen affinity chromatography
RUO
Antibody
Polyclonal
Human
Western Blot
1 mg/mL
PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4
Q15464
SHB; SH2 domain-containing adapter protein B
Rabbit
IgG
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
6461
Documents
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