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Phospho-Sp1 (Ser101) Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen Phospho-Sp1 (Ser101)
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2831 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39758
10 μL
Each for $135.30
Add to cart
 
50-199-2830 Non-distribution product as customer accommodation.
View Documents
Active MotifSupplier Diversity Partner
39757
100 μL
Each for $534.00
Add to cart
 
Description

Description

SP1 is a transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.
Specifications

Specifications

Polyclonal
Primary
Phospho-Sp1 (Ser101)
Unconjugated
SDS
Product Certifications
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