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Phospho-STAT5A/B (Tyr694, Tyr699) Rabbit anti-Human, Unconjugated, Polyclonal, Active Motif™ Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

$135.30 - $534.00

Specifications

Monoclonal or Polyclonal Polyclonal
Primary or Secondary Primary
Antigen Phospho-STAT5A/B (Tyr694, Tyr699)
Conjugate Unconjugated
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Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
50-199-2738 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39618
10 μL
Each for $135.30
Add to cart
 
50-199-2737 Non-distribution product as customer accommodation.
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Active MotifSupplier Diversity Partner
39617
200 μL
Each for $534.00
Add to cart
 
Description

Description

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of, many cell ligands, such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/ BCL-X(L), which suggests the antiapoptotic function of this gene in cells.
Specifications

Specifications

Polyclonal
Primary
Phospho-STAT5A/B (Tyr694, Tyr699)
Unconjugated
SDS
Product Certifications
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