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Phospho-WNK11 (T60) Rabbit anti-Human, Clone: 1259F, R&D Systems™

Rabbit Monoclonal Antibody

$125.35 - $329.00

Specifications

Antigen WNK1
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with Sodium Azide
Format Purified
Clone 1259F
Applications Western Blot
View More Specs

Products 2
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Quantity Price Quantity & Availability  
MAB4720SP View Documents R&D Systems
MAB4720SP
25 ug Each for $125.35
Add to cart
 
MAB4720100 View Documents R&D Systems
MAB4720100
100 ug Each for $329.00
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Description

Description

With No Lysine (K) 1 (WNK1) belongs to a novel family of serine/threonine protein kinases involved in regulating ion transport. The WNKs contain a cysteine instead of the usual lysine in their kinase activation domains. WNK1 mutations have been implicated in Pseudohypoaldosteronism type II (PHAII), an autosomal dominant disorder characterized by hypertension, increased renal salt absorption, and impaired potassium and hydrogen excretion. WNK1 is phosphorylated by Akt1 and Akt2 at T60, and may function as a negative regulator of insulin-stimulated mitogenesis.
Specifications

Specifications

WNK1
Purified
Western Blot
Rabbit
Protein A or G purified from cell culture supernatant
RUO
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with Sodium Azide
1259F
Unconjugated
IgG
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
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