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Sigma Aldrich Photocol(tm)-rut Methacrylated Collagen Bioink Kit With Ruthenium

Catalog No. 9178341EA Shop All MilliporeSigma Sigma Organic Chemistry Products
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91-783-41EA 1 Ea.
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Catalog No. 91-783-41EA Supplier Sigma Aldrich Supplier No. 9178341EA
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MilliporeSigma Sigma Organics products encompass a wide range of quality reagents, solvents, catalysts, and building blocks for organic synthesis. From benchtop discovery to process development and scale-up, Sigma Organics solutions are built to meet the needs of synthetic chemists.

PhotoCol(TM)-RUT bioink kit consists of purified methacrylated Type I bovine collagen as the core component with other support reagents. The methacrylated Type I collagen is produced from telo-peptide intact bovine collagen where the collagen has been modified by reacting the free amines, primarily the epsilon-amines groups of the lysine residues as well as the alpha-amines groups on the N-termini. Over 20% of the total lysine residues of the collagen molecule have been methacrylated. A bottle of 20 mM acetic acid solution is provided to solubilize the lyophilized methacrylated collagen at concentrations ranging from 3 to 8 mg/ml. The neutralization solution consists of an alkaline 10X phosphate buffered saline (PBS) solution which provides physiological salts and pH in the final mixture. The photoinitiator consists of ruthenium and sodium persulfate to be formulated in 1X cell culture media or PBS, which allows visible light photocrosslinking of the printed structure at 400-450 nm. PhotoCol(TM)-RUT provides native-like 3D collagen gels, and the final gel stiffness can be customized by changing collagen concentrations and crosslinking.PhotoCol is a trademark of Advanced BioMatrix, Inc.

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Quantity 1 Ea.
Synonym 3 D Bioprinting; Bioink; Collagen
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