Invitrogen™ PHOX2B Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529025

Catalog No. PIPA529025

Description

Recommended positive controls: 293T, A431, HeLaS3. Predicted reactivity: Mouse (100%), Xenopus laevis (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.

Specifications

• Antigen: PHOX2B
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: PHOX2B
• Gene Alias: dilated pupils 1; Dilp1; GENA 269; LOW QUALITY PROTEIN: paired mesoderm homeobox protein 2B; NBLST2; NBPhox; neuroblastoma paired-type homeobox protein; neuroblastoma Phox; paired like homeobox 2B; paired mesoderm homeobox 2b; paired mesoderm homeobox protein 2B; Paired-like homeobox 2B; PHOX2B; PHOX2B homeodomain protein; Pmx2b
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 8929
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 1 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q99453
• Gene Symbols: PHOX2B
• Immunogen: Synthetic peptide corresponding to a region within amino acids 12 and 107 of PHOX2B.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG