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Thermo Scientific™ DSS (disuccinimidyl suberate), No-Weigh™ Format

Crosslink amines to amines with disuccinimidyl suberate composed of NHS-ester groups with a membrane-permeable, mid-length spacer for intracellular protein crosslinking.

Manufacturer:  Thermo Scientific™ A39267

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Catalog No. PIA39267


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Description

Description

Thermo Scientific™ Pierce DSS, also called disuccinimidyl suberate, is noncleavable and membrane permeable crosslinker that contains an amine-reactive N-hydroxysuccinimide (NHS) ester at each end of an 8-carbon spacer arm.

  • Reactive groups: NHS ester (both ends)
  • Reactive towards: amino groups (primary amines)
  • Amine reactive sulfo-NHS ester reacts rapidly with any primary amine-containing molecule
  • Membrane-permeable, allowing for intracellular crosslinking
  • High purity, crystalline reagent can be used to create high-purity conjugates
  • Non-cleavable
  • Water-insoluble (dissolve first in DMF or DMSO); compare to BS3 (Sulfo-DSS)
Specifications

Specifications

Cell-Permeant
Homobifunctional
Pierce™
Qualified for Ambient or Wet Ice
Short, 11.4 angstroms
Store desiccated at 4°C.
Chemical Labeling
NHS Ester
DMF (Dimethylformamide), DMSO (Dimethylsulfoxide)
Amine
SDS
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