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PIK3C2A Monoclonal Antibody (OTI3C10), TrueMAB™, OriGene
SDP

Mouse Monoclonal Antibody

Supplier:  OriGene TA801643

Encompass_Preferred

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Catalog No. 50-167-8910


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Description

Description

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to omolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Specifications

Specifications

PIK3C2A
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
O00443
PIK3C2A
Human recombit protein fragment corresponding to amino acids 230-560 of human PIK3C2A produced in E.coli.
100 μL
Primary
Human
Antibody
IgG1
Western Blot
OTI3C10
Unconjugated
PIK3C2A
CPK, PI3-K-C2(ALPHA), PI3-K-C2A, PI3K-C2-alpha, PI3K-C2alpha
Mouse
Affinity Chromatography
RUO
5286
-20° C, Avoid Freeze/Thaw Cycles
Liquid
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