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PIK3C2A Mouse anti-Human, Clone: OTI2C2, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA526506

Catalog No. PIMA526506


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Description

Description

The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The PI3-kinase activity of this protein is not sensitive to omolar levels of the inhibitor wortmanin. This protein was shown to be able to be activated by insulin and may be involved in integrin-dependent signaling.
Specifications

Specifications

PIK3C2A
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
O00443
CPK, PI3-K-C2(ALPHA), PI3-K-C2A, C2-containing phosphatidylinositol kinase, PI3K-C2-alpha, PI3K-C2alpha, phosphatidylinositol-4-phosphate 3-kinase C2 domain-containing subunit alpha, phosphoinositide 3-kinase-C2-alpha, ptdIns-3-kinase C2 subunit alpha
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
5286
Immunohistochemistry (Paraffin), Western Blot
OTI2C2
Unconjugated
PIK3C2A
Liquid
PIK3C2A
Human recombit protein fragment corresponding to amino acids 230-560 of PIK3C2A produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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