Pim2 Mouse anti-Human, Active Motif™
Mouse Recombinant Monoclonal Antibody
Manufacturer: Active Motif 91239
DescriptionPIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM-2 overexpression promotes resistance to a host of apoptotic stimuli; its expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.
|-20°C, Avoid Freeze/Thaw Cycles|
|140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5|
|DXCch3; PIM2; Pim-2; pim-2 oncogene; Pim-2 proto-oncogene, serine/threonine kinase; Pim-2h; proto-oncogene Pim-2 (serine threonine kinase); proviral integration site 2; serine/threonine protein kinase pim-2; Serine/threonine-protein kinase pim-2|
|This antibody was raised against a recombinant protein corresponding to human PIM2 (pim-2 oncogene).|
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