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PITPNB Mouse anti-Human, Clone: OTI5D11, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer:  Invitrogen MA527130

Catalog No. PIMA527130


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Description

Description

The lipid binding proteins known as phosphatidylinositol transfer proteins (PITP) facilitate the formation of phosphatidylinositol derived second messenger molecules, which are related to the phospholipase C and phosphoinositide 3-kinase pathways. PITP are ubiquitously expressed proteins that transfer phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes enriched in PI or PC to membranes that are deficient in PI or PC. PITP mobilizes PI from the endoplasmic recticulum and regulates the release of PI from stored vesicles in the Golgi network. In mammalian cells, three smaller forms of soluble PITP are present, designated PITP alpha, PITP beta and retinal degeneration B (rdgB) beta. PITP beta is a 271 amino acid protein that is widely expressed in various tissues. Though required for Golgi targeting, constitutive phosphorylation of Ser-262 has no effect on phospholipid transfer activity. There are two isoforms of PITP beta that are produced as a result of alternative splicing events.
Specifications

Specifications

PITPNB
Monoclonal
1 mg/mL
PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
P48739
PI-TP-beta, PtdInsTP, VIB1B, PtdIns transfer protein beta, phosphatidylinositol transfer protein beta isoform, phosphotidylinositol transfer protein, beta, ptdInsTP beta
Mouse
IgG1
100 μL
-20° C, Avoid Freeze/Thaw Cycles
Primary
23760
Immunohistochemistry (Paraffin), Western Blot
OTI5D11
Unconjugated
PITPNB
Liquid
PITPNB
Full length human recombit protein of PITPNB produced in E.coli
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Documents
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