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PKC 412, Tocris Bioscience™

Catalog Number 29921
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Quantity:
1 mg
This item is not returnable. View return policy
120685-11-2
C35H30N4O4
570.65
MFCD12828879
IIQIEMHSDLLZQA-QZPVEUDVSA-N
[9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrro
101631538
N-[(15R,16S,17R,18S)-17-methoxy-17,18-dimethyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),7(27),8,10,12,20(25),21,23-nonaen-16-yl]-N-methylbenzamide
CO[C@]1(C)[C@@H]([C@H]2O[C@]1(C)N1C3=C(C=CC=C3)C3=C1C1=C(C4=CC=CC=C4N21)C1=C3CNC1=O)N(C)C(=O)C1=CC=CC=C1
This item is not returnable. View return policy
120685-11-2
C35H30N4O4
570.65
MFCD12828879
IIQIEMHSDLLZQA-QZPVEUDVSA-N
[9S-(9α,10β,11β,13α)]-N-(2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-1-oxo-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrro
101631538
N-[(15R,16S,17R,18S)-17-methoxy-17,18-dimethyl-5-oxo-28-oxa-4,14,19-triazaoctacyclo[12.11.2.1¹⁵,¹⁸.0²,⁶.0⁷,²⁷.0⁸,¹³.0¹⁹,²⁶.0²⁰,²⁵]octacosa-1(26),2(6),7(27),8,10,12,20(25),21,23-nonaen-16-yl]-N-methylbenzamide
CO[C@]1(C)[C@@H]([C@H]2O[C@]1(C)N1C3=C(C=CC=C3)C3=C1C1=C(C4=CC=CC=C4N21)C1=C3CNC1=O)N(C)C(=O)C1=CC=CC=C1

Description

Protein kinase C inhibitor

Broad spectrum protein kinase inhibitor. Inhibits conventional PKC isoforms (α, α, γ), PDFRα, VEGFR2, Syk, PKCη, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1, EGFR and MARK (microtubule affinity regulating kinase). Displays potent antitumor activity. Identified as targeting human host cell proteins that interact with SARS-CoV-2.
Quantity 1 mg
Formula Weight 570.64
Percent Purity >98%
Chemical Name or Material PKC 412

Safety and Handling

Recommended Storage Store at -20°C
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