PKC mu Polyclonal Antibody, Invitrogen™

Rabbit Polyclonal Antibody

Supplier:  Thermo Scientific PA513749

Catalog No. PIPA513749

Description

PKC mu (protein kinase C mu, PRKD1) is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway. In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCu. Phosphorylation at Ser916 correlates with PKD/PKCu catalytic activity. PKC mu is one of the PKC family members, and the protein binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface. Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways.

Specifications

• Antigen: PKC mu
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene Accession No.: Q15139, Q62101
• Gene Symbols: PRKD1
• Immunogen: KLH conjugated synthetic peptide between 361-389 amino acids from the N-terminal region of human PKC mu
• Quantity: 400 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 2 mg/mL
• Gene: PRKD1
• Gene Alias: Serine/threonine-protein kinase D1; nPKC-D1; Protein kinase C mu type; nPKC-mu; Protein kinase D; PRKD1; PKD; PKD1; PRKCM
• Host Species: Rabbit
• Purification Method: Ammonium sulfate precipitation, Size-exclusion - Dialysis
• Regulatory Status: RUO
• Gene ID (Entrez): 18760, 5587
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Liquid