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PKC mu Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Supplier: Thermo Scientific PA513749
SDSDocumentsProduct Certifications Promotions
DescriptionPKC mu (protein kinase C mu, PRKD1) is a serine/threonine kinase whose activation is dependent on the phosphorylation of two activation loop sites, Ser744 and Ser748, via a PKC-dependent signaling pathway. In addition to the two activation loop sites, the carboxy-terminal Ser916 has been identified as an autophosphorylation site for PKD/PKCu. Phosphorylation at Ser916 correlates with PKD/PKCu catalytic activity. PKC mu is one of the PKC family members, and the protein binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface. Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways.
|KLH conjugated synthetic peptide between 361-389 amino acids from the N-terminal region of human PKC mu|
|Immunohistochemistry (Paraffin), Western Blot|
|Serine/threonine-protein kinase D1; nPKC-D1; Protein kinase C mu type; nPKC-mu; Protein kinase D; PRKD1; PKD; PKD1; PRKCM|
|Ammonium sulfate precipitation, Size-exclusion - Dialysis|
|-20° C, Avoid Freeze/Thaw Cycles|
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