Plakophilin 3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Manufacturer: Proteintech Group Inc 183381AP
DescriptionPlakophilin-3 is an Armadillo-like protein present in nuclei and desmosomes of epithelial cells. The expression pattern of this protein seems to be largely restricted to epithelial cell types. Plakophilin-3 can be detected along cell borders in a punctuate staining pattern typical for desmosomal proteins. In addition to the desmosomal immunolocalization, immunostaining was observed as bright nuclear speckles. Thus, like plakophilin-1 and-2, plakophilin-3 displays a dual intracellular localization in the desmosomal plaque and in the cell nucleus, and therefore is probably involved in signal transduction pathways between the plasma membrane and the nucleus. The human protein has a predicted molecular mass of ~87 kDa.
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|PKP3, plakophilin 3|
|11187, 293619, 56460|
|Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot|
|Plakophilin 3 Fusion Protein Ag13062|
|Antigen Affinity Chromatography|
|Human, Mouse, Rat|
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