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PLAP Rabbit anti-Human, Mouse, Polyclonal, Proteintech Non-distribution product as customer accommodation.

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group IncSupplier Diversity Partner 185071AP

Catalog No. 50-173-2173


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Description

Description

Placental Alkaline Phosphatase plays an important role in the regulation of specific inflammatory disease processes. There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney for this form of alkaline phosphatase have been well characterized.Placental Alkaline Phosphatase reacts with a membrane-bound isoenzyme (Regan and Nagao type) of Placental Alkaline Phosphatase (PLAP) occurring in the placenta during the 3rd trimester of gestation. Placental Alkaline Phosphatase is useful in the identification of testicular germ cell tumors. Unlike germ cell tumors, PLAP-positive somatic cell tumors uniformly express epithelial membrane antigen (EMA). A proposed function of Placental Alkaline Phosphatase is matrix mineralization; however, mice that lack a functional form of this enzyme show normal skeletal development. Placental Alkaline Phosphatase has been linked directly to hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of hypophosphatasia can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.
Specifications

Specifications

PLAP
0.13 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
P05187
ALP, ALPP, PALP, Placental alkaline phosphatase, PLAP, PLAP 1
Rabbit
IgG
150 μL
-20°C
Primary
250
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
ALPP
Liquid
ALPP
PLAP Fusion Protein Ag13361
Antigen Affinity Chromatography
RUO
Antibody
Polyclonal
Human, Mouse
Documents
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