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Thermo Scientific™ Lab Vision™ Plastin-L Ab-1, Mouse Monoclonal Antibody

Provide accurate, reproducible results with the Thermo Scientific™ Plastin-L Ab-1, Mouse Monoclonal Antibody.

Specifications

Antigen Plastin-L Ab-1
Clone LPL4A.1
Applications Immunofluorescence, Immunoprecipitation, Western Blot
Classification Monoclonal
Conjugate Unconjugated
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Products 1
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
Catalog Number Mfr. No. Concentration Quantity Price Quantity & Availability  
MS1326P1
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Thermo Scientific™
MS1326P1
200μg/mL 500μL This item has been discontinued by the manufacturer and is no longer available. Please call customer service for assistance: 1-800-766-7000.
N/A
Description

Description

Provide accurate, reproducible results with the Thermo Scientific™ Plastin-L Ab-1, Mouse Monoclonal Antibody.

L-plastin is a leukocyte specific actin bundling protein from fimbrin family of proteins. It has two actin-binding domains and two EF hand type calcium-binding domains. It gets phosphorylated on the serine residue in its headpiece region in response to a variety of inflammatory stimuli. It is hypothesized that L-plastin may play a role in regulating integrin mediated adhesion in leukocytes. L-plastin is expressed in majority of human cancer cell lines derived from solid tumors. Its expression is positively upregulated by testosteronse in andrgen receptor positive prostrate and breast cancer cells through three androgen receptor binding elements located in the upstream region of the gene.

Host Species: Mouse

Clone: LPL4A.1

Isotype: IgG1

Species Reactivity: Human. Does not react with Mouse. Others not known.

Epitope: Headpiece region

Immunogen: Human recombinant L-plastin protein

Molecular Weight: 62kDa

Positive Control: Human polymorphonuclear neutrophils and monocytes, MCF-7, Jurkat cells

Cellular Localization: Cytoplasmic

Recommended for:

  • Western Blotting
  • Immunofluorescence (Fixed in methanol or 3% paraformaldehyde)
  • Immunoprecipitation (Native)

Note:

USA: RUO; Int'l: RUO

Specifications

Specifications

Plastin-L Ab-1
Immunofluorescence, Immunoprecipitation, Western Blot
Unconjugated
Murine
Cytoskeletal Protein
Human recombinant L-plastin protein
LPL4A.1
Monoclonal
Concentrated
RUO
Primary
IgG1
SDS
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