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PLAT Mouse anti-Human, Clone: OTI3H3, lyophilized, TrueMAB™ Non-distribution product as customer accommodation.

Mouse Monoclonal Antibody

Manufacturer:  OriGeneSupplier Diversity Partner CF805448

Catalog No. 50-166-7432


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Description

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

PLAT gene encodes tissue-type plasminogen activator, a secreted serine protease that converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. The encoded preproprotein is proteolytically processed by plasmin or trypsin to generate heavy and light chains. These chains associate via disulfide linkages to form the heterodimeric enzyme. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, while decreased activity leads to hypofibrinolysis, which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Specifications

Specifications

PLAT
Monoclonal
Unconjugated
PLAT
Lyophilized
PLAT
Human recombit protein fragment corresponding to amino acids 157-426 of human PLAT produced in E.coli.
Affinity Chromatography
RUO
Antibody
Monoclonal
Human
Immunohistochemistry (Paraffin), Western Blot
OTI3H3
PBS with 8% trehalose and no preservative; pH 7.3
P00750
T-PA, TPA
Mouse
IgG2b
100 μg
-20° C, Avoid Freeze/Thaw Cycles
Primary
5327
SDS
Documents
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