Invitrogen™ PLCZ1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA550476

Catalog No. PA550476

Description

The antibody detects endogenous levels of total PLCZ1 protein.

The protein encoded by this gene is a member of the phosphoinositide-specific phospholipase C family. Members in this family, classified into six isotypes that are tissue- and organ-specific, hydrolyze phosphatidylinositol 4,5-bisphosphate just before the phosphate group to yield diacylglycerol and inositol 1,4,5-trisphosphate. This protein localizes to the acrosome in spermatozoa and elicits Ca(2+) oscillations and egg activation during fertilization that leads to early embryonic development. Alternative splicing results in multiple transcript variants.

Specifications

• Antigen: PLCZ1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: Plcz1
• Gene Alias: 1700041H07Rik; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase zeta-1; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase zeta-1; NYD-SP27; Phosphoinositide phospholipase C-zeta-1; phospholipase C zeta; phospholipase C zeta 1; phospholipase C, zeta 1; phospholipase C-zeta-1; phospholipase C-zeta-1 {ECO:0000250; PI-phospholipase C zeta 1; PLCZ1; plcz1 {ECO:0000312; PLCzeta; PLC-zeta-1; PLC-zeta-1 {ECO:0000250; RGD:1359567}; testicular tissue protein Li 145; Testis-development protein NYD-SP27; testis-development related NYD-SP27; UniProtKB:Q86YW0}
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 89869
• Content And Storage: -20°C
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 1.3 mg/mL
• Formulation: PBS with 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q86YW0
• Gene Symbols: Plcz1
• Immunogen: Fusion protein corresponding to residues near the C terminal of human phospholipase C, zeta 1.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG